It could be set up in not more than 1/2 hour if organized and certainly with practice. I'm not sure how long it took me to set it up this very first time.
We car-topped it on my wife's Subaru and were pretty well organized but not completely organized. We drove down a boat ramp and then had to carry everything a short ways to the shore. That was okay.
What would be most efficient would be to keep the boat on a trailer, rig it away from the water, and then take it down fully rigged. A trailer I have my eye on is the 147 lb aluminum Trailex SUT-220-S:
https://www.trailex.com/SUT-220-S.cfm. I had a larger Trailex trailer for a pretty good sized sailboat that I built years ago.
The problem with a trailer is it needs to be stored. I have room, but I consider a boat on a trailer to be an eyesore that needs to be hid. Also, the boat sits upright on the trailer and would need to be covered. For sure a packrat or other animal would live in that and create a mess in a hurry.
So another option is to rig the canoe on shore (in a parking lot, for example) and haul it down to the water with a small canoe dolly. I actually bought an axle and probably wheels years ago to make one. I kind of forgot about it. I need to go look for them.
Anyway, the short answer is it should be less than 1/2 hour to rig or unrig.