You should never run a fuel injected vehicle below 1/4 tank of gas.The fuel pump is in the gas tank and under 1/4 of gas it is no longer sumerged in fuel which cools the pump,you will fry the pump faster running it that low.You also will start to suck up all that junk that will get sucked into the fuel filter clogging it faster and at $120 for the fuel filter and having to drop the gas tank(it sits on top) I wouldn't want to go that low very often.Then again I never drop below a 1/2 tank of gas,it also doesn't "seem" to hit the wallet as bad that way also.

My 2 cents.