Just removed the factory renegade rock rails this weekend and added some new rock sliders. As a result, there are a few holes in my frame with nothing in them.

Do I need to patch the old holes or is it safe to leave them?

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"I don't know what's gonna happen man, but I wanna get my kicks before the whole $#!+house goes up in flames." -Jim Morrison

You mean where the nut inserts are? If worried about them, put the bolts back in them.

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2005 Liberty Renegade, Bright Silver Metallic

You can do as Leeann stated or just forget about them ,
won't hurt anything really

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MUDD'S MOTORSPORT'S We do IFS lift installs ,
03 OVERLAND EDITION /Kilby-Skidrow-Mopar-4XGuard skids/ 2.5 inch TOTAL CONTROL JBA coilovers -JBA Arms/MOABS-31 FALKEN WILDPEAK AT3W / 4.10's etc, 04 Kilimanjaro Edition loaded, plus 05 KJ limited